Claude Science-style research workbench: ReAct research-loop engine (research_* tools), versioned artifacts with provenance (artifact_* tools), and 10 science skills for genomics/pathogens/bioinformatics.
Install
# from GitHub (first run asks for allowBuilds approval — follow the hint, retry)
dsh plugin --profile web add github:biociao/dsh-science
GitHub-sourced plugins run build scripts on your machine at install time. Only install sources you trust, and pin a commit (github:owner/repo#sha).
README
A Claude Science–style research workbench for DeepSeek Harness — for genomics / pathogens / human health / bioinformatics projects.
One-liner: dsh-science — Claude Science-style research workbench for DSH: ReAct research-loop engine (research_* tools), versioned artifacts with provenance (artifact_* tools), and 10 science skills for genomics / pathogens / bioinformatics.
- ReAct research loop engine —
research_init/research_state/research_hypothesis/research_experiment/research_findings/research_phase/research_review, persisted in aresearch-manifest.jsonstate machine (Question → Hypothesis → Experiment → Observe → Analyze → Conclude → Next Question). - Versioned artifacts with provenance —
artifact_save/artifact_list/artifact_show/artifact_reproduce: every result saved asartifacts/<name>/v<N>/with per-file SHA-256,artifact.jsonprovenance (command / inputs / notes / environment) and an append-onlyprovenance.md. - 10 science skills — research-loop, science-project-setup, artifact-provenance, scientific-reviewer, literature-connector, parallel-delegation, manuscript-writing, bioinformatics-toolkit, conda-environments, data-inventory.
Both engine plugins are zero-dependency (Node built-ins only) and register plain cordis tools. Installable either as a profile bundle (dsh plugin add) or as an agent preset (科学模式).
Install
Option A — profile bundle (community standard)
dsh plugin --profile web add dsh-science # after npm publish
# or straight from GitHub:
dsh plugin --profile web add "github:biociao/dsh-science"
Restart the profile (or refresh the Web GUI). The bundle inserts the two engines
into the profile layer stack; the research_* / artifact_* tools become
available to every agent on that profile.
Option B — agent preset (full 科学模式 experience, per-agent)
git clone https://github.com/biociao/dsh-science ~/.dsh/.agent-presets/science
# or from a local checkout:
bash scripts/install.sh # copy (or: bash scripts/install.sh link)
Then create a session in the DSH Web GUI and pick the 科学模式 preset — the preset carries the research persona + engines with per-agent scoping.
Skills
The 10 skills are discovered automatically from a project's .dsh/skills/
(drop this repo's skills/ into your project), or install them machine-wide:
bash scripts/install-skills.sh # -> ~/.dsh/skills (respects $DSH_HOME)
Quick start (first session)
research_init— createresearch-manifest.json+ the project skeleton (experiments/ literature/ artifacts/ analyses/ figures/ manuscript/ reviews/ data/ envs/).- Read
research_stateat the start of every session; the loop state persists across sessions. - Run the loop:
research_hypothesis(H1/H2/…) →research_experiment(E01/…, createsexperiments/<id>/{design.md,log.md,code/,results/}) → run code →research_findings(appends to log.md, updates hypothesis status, advances the loop) →artifact_savefor anything worth citing or reproducing. - For key claims: extract the claim, have a review subagent check it against the
execution records (see the
scientific-reviewerskill), archive withresearch_review(writesreviews/R0n/report.md).
Repository layout
dsh-science/
├── package.json # dsh.bundle.patch -> ./cordis.patch.yml (+ exports)
├── cordis.patch.yml # bundle patch: inserts the two engines by subpath export
├── engines/ # canonical engine sources (bundle form)
│ ├── research-loop.mjs
│ └── artifact-registry.mjs
├── preset/ # agent-preset form (mirrors engines/ via sync-engines.sh)
│ ├── agent.cordis.yml # references ./engines/*.mjs (relative, preset mount)
│ ├── preset.yml
│ └── engines/ # mirror — keep in sync: bash scripts/sync-engines.sh
├── skills/ # 10 SKILL.md skills
├── scripts/
│ ├── install.sh # install preset -> ~/.dsh/.agent-presets/science
│ ├── install-skills.sh # install skills -> ~/.dsh/skills
│ ├── sync-engines.sh # mirror engines/ -> preset/engines/
│ ├── init-project.sh # project skeleton without a science session
│ └── smoke-test.mjs # 23 checks against a temp workspace (node >= 18)
└── test/verify-bundle.sh # isolated end-to-end bundle install + boot check
Verification
node scripts/smoke-test.mjs # engine logic + end-to-end loop against a temp workspace
bash test/verify-bundle.sh # pnpm pack -> isolated profile -> install -> boot check
Both are part of the release checklist and are safe to run in CI (the smoke test
writes only to a temp workspace; the bundle test uses an isolated $DSH_HOME).
FAQ
Why subpath exports and not relative paths in the bundle?
dsh plugin add installs the package into the profile and its cordis.patch.yml
rows join the profile composition. The profile loader resolves a row name
relative to the profile directory (not the package), so ./engines/x.mjs
fails with ERR_MODULE_NOT_FOUND. Referencing dsh-science/engines/x.mjs
(subpath export, exports in package.json) resolves from the profile's
node_modules and works — verified experimentally on dsh 0.1.0-rc.6.
The agent-preset mount, by contrast, resolves relative names from the preset
directory, which is why preset/agent.cordis.yml can use ./engines/*.mjs.
Bundle or preset — which should I use?
- Bundle: tools available to every agent on the profile; one command to install.
- Preset: the full 科学模式 experience (research persona, per-agent scoping).
The persona row in
cordis.patch.ymlis commented out because a profile-wide persona would apply to all agents — uncomment it before publishing if that is what you want.
Where do the skills come from?
A project's .dsh/skills/ is auto-discovered; scripts/install-skills.sh puts
them machine-wide in ~/.dsh/skills (respecting $DSH_HOME).
Development
bash scripts/sync-engines.sh # after editing engines/*.mjs — keeps preset/engines in sync
node scripts/smoke-test.mjs # logic + static package checks
bash test/verify-bundle.sh # end-to-end bundle install + boot
Community
- Topic: github.com/topics/dsh-plugin
- Curated lists: awesome-dsh-plugin · awesome-deepseek-harness
License
MIT — see LICENSE.
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